Xanthine oxidase-IN-14
Xanthine oxidase-IN-14 (Compound 3f) is an inhibitor for xanthine oxidase, with IC50 >100 μM. Xanthine oxidase-IN-14 inhibits proliferations of cancer cells MCF-7, NCI-H460 and SF-268, with IC50 greater than 150 μM[1].
Product Specifications
CAS Number
[80025-67-8]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Xanthine Oxidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/xanthine-oxidase-in-14.html
Solubility
10 mM in DMSO
Smiles
N#CC1=C(N)N(C2=CC=C(C(F)(F)F)C=C2)N=C1
Molecular Formula
C11H7F3N4
Molecular Weight
252.20
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Gupta S, et al., Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors. Eur J Med Chem. 2008 Apr;43 (4) :771-80.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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