IHMT-PI3K-315
IHMT-PI3K-315 (20e) is a potent and selective PI3Kγ/δ inhibitor with IC50 values for PI3Kγ and PI3Kδ of 4.0 and 9.1 nM, respectively. IHMT-PI3K-315 has antitumor activity[1].
Product Specifications
UNSPSC
12352211
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ihmt-pi3k-315.html
Smiles
FC(OC1=C(N=CC(C2=CC3=CC(NC(NCCOC4=CN=CC=C4)=O)=NN3C=C2)=C1)OC)F
Molecular Formula
C22H20F2N6O4
Molecular Weight
470.43
References & Citations
[1]Wang C, et al. Discovery of Pyrazolo[1,5-a]pyridine Derivatives as Potent and Selective PI3Kγ/δ Inhibitors. J Med Chem. 2024 Sep 12;67 (17) :15199-15219.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kγ; PI3Kδ
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