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SPLA2-IIA Inhibitor

This cyclic pentapeptide analog, c2 (cyclic 2-Nal-Leu-Ser-2-Nal-Arg), is a specific inhibitor of human group IIA secreted phospholipase A2 (sPLA2-IIA) . It blocks the enzyme's hydrolysis of the sn-2 ester bond in phospholipids, thereby inhibiting the release of pro-inflammatory mediators like arachidonic acid, making it a valuable tool for studying sPLA2-IIA in inflammatory and cardiovascular disease research models.

Product Specifications

Field of Research

Metabolism Research; Pharmacology & Drug Discovery

Molecular Weight

750.89

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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