SPLA2-IIA Inhibitor
This cyclic pentapeptide analog, c2 (cyclic 2-Nal-Leu-Ser-2-Nal-Arg), is a specific inhibitor of human group IIA secreted phospholipase A2 (sPLA2-IIA) . It blocks the enzyme's hydrolysis of the sn-2 ester bond in phospholipids, thereby inhibiting the release of pro-inflammatory mediators like arachidonic acid, making it a valuable tool for studying sPLA2-IIA in inflammatory and cardiovascular disease research models.
Product Specifications
Field of Research
Metabolism Research; Pharmacology & Drug Discovery
Molecular Weight
750.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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