Tecaginlimab
Tecaginlimab (BNT-312) is a Fc-inert bispecific antibody for dual targeting and conditional stimulation of CD40 and 4-1BB. Tecaginlimab can enhance priming and reactivation of tumor-specific immunity[1].
Product Specifications
CAS Number
[2253891-70-0]
Product Name Alternative
BNT-312; DuoBody-CD40x-4-1BB; GEN1042
UNSPSC
12352203
Target
TNF Receptor
Type
Inhibitory Antibodies
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tecaginlimab.html
Purity
99.00
Solubility
H2O
Smiles
[Tecaginlimab]
Molecular Weight
(145.098 kDa)
References & Citations
[1]Muik A, et, al. DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity. J Immunother Cancer. 2022 Jun;10 (6) :e004322.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
Isoform
TNFRSF5/CD40; TNFRSF9/4-1BB/CD137
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1154303-01 0.02 mg (E-Coli)
Recombinant Bacillus subtilis Uncharacterized protein yqkK (yqkK)
Ask
View Details MBS1154303-02 0.1 mg (E-Coli)
Recombinant Bacillus subtilis Uncharacterized protein yqkK (yqkK)
Ask
View Details