Tecaginlimab

Tecaginlimab (BNT-312) is a Fc-inert bispecific antibody for dual targeting and conditional stimulation of CD40 and 4-1BB. Tecaginlimab can enhance priming and reactivation of tumor-specific immunity[1].

Product Specifications

CAS Number

[2253891-70-0]

Product Name Alternative

BNT-312; DuoBody-CD40x-4-1BB; GEN1042

UNSPSC

12352203

Target

TNF Receptor

Type

Inhibitory Antibodies

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tecaginlimab.html

Purity

99.00

Solubility

H2O

Smiles

[Tecaginlimab]

Molecular Weight

(145.098 kDa)

References & Citations

[1]Muik A, et, al. DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity. J Immunother Cancer. 2022 Jun;10 (6) :e004322.