L 651142
L 651142 is a weak platelet activating factor (PAF) receptor antagonist. L 651142 inhibits the binding of [3H]PAF to rabbit platelet, human platelet or human lung membranes with Kis of 0.839 μM, 1.82 μM, 3.64 μM, respectively[1].
Product Specifications
CAS Number
99046-40-9
UNSPSC
12352005
Target
Platelet-activating Factor Receptor (PAFR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-651142.html
Smiles
COCCC(C1=CC(OC)=CC=C1/2)=C(C)C2=C/C3=CC=C(C=C3)S(N)(=O)=O
Molecular Formula
C21H23NO4S
Molecular Weight
385.48
References & Citations
[1]S B Hwang, et al. Species difference in the specific receptors of platelet activating factor. Biochem Pharmacol. 1986 Dec 15;35 (24) :4511-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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