Recombinant Human TNF-related Weak Inducer of Apoptosis Receptor/TNFRSF12A
Recombinant Human TNF-related Weak Inducer of Apoptosis Receptor/TNFRSF12A
Product Specifications
Product Name Alternative
TNFRSF12A, FGF-inducible 14, CD266
UniProt
Q9NP84
Source
Escherichia coli
Field of Research
Immunology & Inflammation; Cell Biology
Endotoxin
Less than 1 EU/ug of rHuTWEAK Receptor as determined by LAL method.
Purity
> 95 % by SDS-PAGE and HPLC analyses.
Bioactivity
Fully biologically active when compared to standard. The ED50 as determined by inhibiting TWEAK-dependent proliferation of human umbilical vein endothelial cells (HUVEC) is less than 30 ng/ml, corresponding to a specific activity of > 3.3 x104 IU/mg, in the presence of 15 ng/ml of rHuTWEAK.
Form
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Molecular Weight
Approximately 5.6 kDa, a single non-glycosylated polypeptide chain containing 53 amino acids.
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Notes
For research use only.
AA Sequence
EQAPGTAPCS RGSSWSADLD KCMDCASCRA RPHSDFCLGC AAAPPAPFRL LWP
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