Recombinant Human Insulin-like Growth Factor-Binding Protein 3
Recombinant Human Insulin-like Growth Factor-Binding Protein 3
Product Specifications
Product Name Alternative
Growth-hormone-dependant Binding Protein, IBP-3, IGF-binding protein 3
UniProt
P17936
Source
Escherichia coli
Field of Research
Metabolism Research; Stem Cell & Developmental Biology
Endotoxin
Less than 1 EU/ug of rHuIGF-BP3 as determined by LAL method.
Purity
> 98 % by SDS-PAGE and HPLC analyses.
Bioactivity
Fully biologically active when compared to standard. The ED50 as determined by inhibiting IGF-II induced proliferation of serum free human MCF-7 cells is less than 200 ng/ml, corresponding to a specific activity of > 5.0 x103 IU/mg in the presence of 15 ng/ml of rHuIGF-II.
Form
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Molecular Weight
Approximately 28.8 kDa, a single non-glycosylated polypeptide chain containing 264 amino acids.
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Notes
For research use only.
AA Sequence
GASSAGLGPV VRCEPCDARA LAQCAPPPAV CAELVREPGC GCCLTCALSE GQPCGIYTER CGSGLRCQPS PDEARPLQAL LDGRGLCVNA SAVSRLRAYL LPAPPAPGNA SESEEDRSAG SVESPSVSST HRVSDPKFHP LHSKIIIIKK GHAKDSQRYK VDYESQSTDT QNFSSESKRE TEYGPCRREM EDTLNHLKFL NVLSPRGVHI PNCDKKGFYK KKQCRPSKGR KRGFCWCVDK YGQPLPGYTT KGKEDVHCYS MQSK
Available Sizes
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