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Recombinant Human Tissue Inhibitor of Metalloproteinases 2

Selected Variant

GTR19033577-01

Size: 10 µg

Recombinant Human Tissue Inhibitor of Metalloproteinases 2

Product Specifications

UniProt

P16035

Source

Escherichia coli

Field of Research

Pharmacology & Drug Discovery

Endotoxin

Less than 1 EU/ug of rHuTIMP-2 as determined by LAL method.

Purity

> 95 % by SDS-PAGE and HPLC analyses.

Bioactivity

Fully biologically active when compared to standard. The biologically active as determined by its ability to inhibit human MMP-2 cleavage of a fluorogenic peptide substrate Mca-PLGL-Dpa-AR-NH2.

Form

Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4, with 3 % trehalose.

Molecular Weight

Approximately 21.8 kDa, a single non-glycosylated polypeptide chain containing 194 amino acids.

Storage Conditions

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Notes

For research use only.

AA Sequence

CSCSPVHPQQ AFCNADVVIR AKAVSEKEVD SGNDIYGNPI KRIQYEIKQI KMFKGPEKDI EFIYTAPSSA VCGVSLDVGG KKEYLIAGKA EGDGKMHITL CDFIVPWDTL STTQKKSLNH RYQMGCECKI TRCPMIPCYI SSPDECLWMD WVTEKNINGH QAKFFACIKR SDGSCAWYRG AAPPKQEFLD IEDP

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