Recombinant Human Tissue Inhibitor of Metalloproteinases 2
Selected Variant
GTR19033577-01
Size: 10 µg
Recombinant Human Tissue Inhibitor of Metalloproteinases 2
Product Specifications
UniProt
P16035
Source
Escherichia coli
Field of Research
Pharmacology & Drug Discovery
Endotoxin
Less than 1 EU/ug of rHuTIMP-2 as determined by LAL method.
Purity
> 95 % by SDS-PAGE and HPLC analyses.
Bioactivity
Fully biologically active when compared to standard. The biologically active as determined by its ability to inhibit human MMP-2 cleavage of a fluorogenic peptide substrate Mca-PLGL-Dpa-AR-NH2.
Form
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4, with 3 % trehalose.
Molecular Weight
Approximately 21.8 kDa, a single non-glycosylated polypeptide chain containing 194 amino acids.
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Notes
For research use only.
AA Sequence
CSCSPVHPQQ AFCNADVVIR AKAVSEKEVD SGNDIYGNPI KRIQYEIKQI KMFKGPEKDI EFIYTAPSSA VCGVSLDVGG KKEYLIAGKA EGDGKMHITL CDFIVPWDTL STTQKKSLNH RYQMGCECKI TRCPMIPCYI SSPDECLWMD WVTEKNINGH QAKFFACIKR SDGSCAWYRG AAPPKQEFLD IEDP
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