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[D-Asp3]-Microcystin-LR

Product Specifications

CAS Number

120011-66-7

UNSPSC Description

Microcystin-[D-Asp3]-LR/Microcystin A is a cyanotoxin. Microcystin-[D-Asp3]-LR/Microcystin A can activate Nrf2 and promote oxidative stress response. Microcystin-[D-Asp3]-LR/Microcystin A can also be used in toxicology research[1][2].

Target Antigen

Keap1-Nrf2

Type

Peptides

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Solubility

10 mM in DMSO

Smiles

CO[C@@H](CC1=CC=CC=C1)[C@@H](C)/C=C(C)/C=C/[C@@H]2NC([C@@H](NC(C[C@@H](NC([C@@H](NC([C@H](NC(C(N(C(CC[C@@H](NC([C@H]2C)=O)C(O)=O)=O)C)=C)=O)C)=O)CC(C)C)=O)C(O)=O)=O)CCCNC(N)=N)=O

Molecular Weight

981.15

References & Citations

[1]Arman T, et al. Microcystin Toxicokinetics, Molecular Toxicology, and Pathophysiology in Preclinical Rodent Models and Humans. Toxins (Basel). 2021 Jul 29;13(8):537. |[2]Lundqvist J, et al. Microcystins activate nuclear factor erythroid 2-related factor 2 (Nrf2) in human liver cells in vitro - Implications for an oxidative stress induction by microcystins. Toxicon. 2017 Feb;126:47-50.

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

Frequently Asked Questions

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