(R) -ZINC-3573
(R) -ZINC-3573 is a selective Mas-related G protein-coupled receptor X2 (MRGPRX2) agonist with an EC50 value of 740 nM. (R) -ZINC-3573 can be used as a MRGPRX2 probe for the research of pain and itch[1].
Product Specifications
CAS Number
[2089389-15-9]
UNSPSC
12352005
Target
Mas-related G-protein-coupled Receptor (MRGPR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/r-zinc-3573.html
Concentration
10mM
Purity
99.83
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CN([C@H]1CN(CC1)C2=CC(C3=CC=CC=C3)=NC4=CC=NN24)C
Molecular Formula
C18H21N5
Molecular Weight
307.39
References & Citations
[1]Lansu K, et al. In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat Chem Biol. 2017 May;13 (5) :529-536.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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