Z-Gly-Pro-Arg-4MβNA

Z-Gly-Pro-Arg-4MβNA is the cleavage of the substrate of thrombin to release free 4-methoxy-2-naphthylamine (4MβNA) . Free 4MβNA can be captured by 5-nitrosalicylaldehyde to produce an insoluble yellow fluorescent and marks the site of thrombin activity[1].

Product Specifications

CAS Number

[66647-41-4]

UNSPSC

12352209

Hazard Statement

H302-H315-H319-H335

Target

Thrombin

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/z-gly-pro-arg-4mβna.html

Solubility

10 mM in DMSO

Smiles

COC1=CC(NC([C@H](CCCNC(N)=N)NC([C@H]2N(CCC2)C(CNC(OCC3=CC=CC=C3)=O)=O)=O)=O)=CC4=C1C=CC=C4

Molecular Formula

C32H39N7O6

Molecular Weight

617.70

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Bushi D, et al. A novel histochemical method for the visualization of thrombin activity in the nervous system. Neuroscience. 2016 Apr 21;320:93-104.