Mouse CD206 Protein, His Tag
CD209 is also known as CLEC4L, DC-SIGN and CD209 antigen. Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates. May act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2. Seems to regulate DC-induced T-cell proliferation by binding to ICAM3 on T-cells in the immunological synapse formed between DC and T-cells.
Product Specifications
UniProt
Q61830
Expression Region
Leu 20 - Ala 1388
Reactivity
Mouse
Conjugation
Unconjugated
Tag
C-10xHis
Field of Research
Immunology & Inflammation
Endotoxin
1.0 EU per μg
Purity
90%
Form
Powder
Molecular Weight
157.3 kDa
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
NCBI Accession Number
Q61830
Preservative
PBS, pH 7.4
Available Sizes
Frequently Asked Questions
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