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Human CD39L1 / ENTPD2 Protein, His Tag (active enzyme, MALS verified)

CD39L1, also known as ENTPD2 and NTPDase2, is an ectonucleotidase belonging to the CD39 family. It is found on the surface of vascular adventitial cells and accessory vascular cells . CD39L1 is a Ca2+ and Mg2+ dependent enzyme that hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP > > ADP = UDP. CD39L1 plays a role in regulating thrombosis and inflammation . It is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation.

Product Specifications

UniProt

Q9Y5L3

Expression Region

Thr 29 - Asp 460

Reactivity

Human

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human CD39L1/ENTPD2 Protein, His Tag (orb1733263) is expressed from CHO cells. It contains AA Thr 29 - Asp 460 (Accession # Q9Y5L3-1) .

Field of Research

Immunology & Inflammation; Cell Biology

Endotoxin

1.0 EU per μg

Purity

95%

Form

Liquid

Molecular Weight

49.0 kDa

Storage Conditions

-70°C

Notes

For research use only.

Applications Notes

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 49.0 kDa. The protein migrates as 36-37 kDa and 57-63 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

NCBI Accession Number

Q9Y5L3

Preservative

20 mM Tris, 150 mM NaCl, pH7.5

Available Sizes

Frequently Asked Questions

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