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Human interleukin 6 (IL-6) 29-212 aa

Interleukin-6 (IL-6) is a 22-28 kDa phosphorylated and variably glycosylated cytokine that plays important roles in the acute phase reaction, inflammation, hematopoiesis and bone metabolism. Mature human IL-6 is 183 amino acids (aa) in length and shares 39% aa sequence identity with mouse IL-6. Aberrant IL-6 activity contributes to chronic inflammation in obesity, insulin resistance, inflammatory bowel disease, arthritis, sepsis, and atherosclerosis.

Product Specifications

Product Name Alternative

B-cell stimulatory factor 2 (BSF-2), CTL differentiation factor (CDF), Hybridoma growth factor

UniProt

P05231

Reactivity

Human, Mouse

Conjugation

Unconjugated

Tag

Histidine

Source

E.coli

Origin

Recombinant protein expressed as His tage protein in E.coli

Field of Research

Immunology & Inflammation

Concentration

1mg/mL

Dilution

NA

Endotoxin

Not tested

Purity

≥85%

Form

Lyophilized

Solubility

Soluble in PBS at 25°C

Molecular Weight

~22 kDa

Storage Conditions

After reconstitution, store at -20°C; Avoid repeated freeze thaw

Notes

For research use only.

Applications Notes

For research use only

Tested Applications

SDS-PAGE

Host or Source

E. coli

Preservative

No preservative

AA Sequence

VPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM

Frequently Asked Questions

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