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Spantide I TFA

Spantide I TFA is a selective NK1 receptor antagonist and substance P analog with a 35-fold selectivity for NK1 (Ki=230 nM) over NK2 receptors. It modulates the corneal cytokine profile by reducing type 1 and increasing IL-10, demonstrating efficacy in reducing corneal perforation in infection models.

Product Specifications

Field of Research

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Molecular Weight

1611.81

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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