Recombinant Human B-Cell Maturation Antigen/TNFRSF17
Recombinant Human B-Cell Maturation Antigen/TNFRSF17
Product Specifications
Product Name Alternative
TNFRSF17, BCM, CD269
UniProt
Q02223
Source
Escherichia coli
Field of Research
Immunology & Inflammation
Endotoxin
Less than 1 EU/ug of rHuBCMA as determined by LAL method.
Purity
> 98 % by SDS-PAGE and HPLC analyses.
Bioactivity
Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated murine B cells is no less than 40 ng/ml, corresponding to a specific activity of > 2.5 x104 IU/mg in the presence of 100 ng/ml human APRIL.
Form
Lyophilized from a 0.2 μm filtered concentrated solution in 30 % acetonitrile, 0.1 % TFA.
Molecular Weight
Approximately 5.4 kDa, a single non-glycosylated polypeptide chain containing 50 amino acids.
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Notes
For research use only.
AA Sequence
AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
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