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Sirt2-IN-1

Sirt2-IN-1 (Compound 9) is a sirtuin 2 (Sirt2) inhibitor with an IC50 of 163 nM[1].

Product Specifications

CAS Number

[1862238-00-3]

UNSPSC

12352005

Target

Sirtuin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Sirt2-IN-1.html

Purity

98.71

Solubility

DMSO : 150 mg/mL (ultrasonic)

Smiles

O=C(NC1=NC=C(CC2=CC=CC(OCC3=CN(CC4=CC=CC=C4)N=N3)=C2)S1)CSC5=NC(C)=CC(C)=N5

Molecular Formula

C28H27N7O2S2

Molecular Weight

557.69

References & Citations

[1]Schiedel M, et al. Structure-Based Development of an Affinity Probe for Sirtuin 2. Angew Chem Int Ed Engl. 2016 Feb 5;55 (6) :2252-6.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

SIRT2

Available Sizes

Curated Selection

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