5-Bromo-5-nitro-1,3-dioxane

5-Bromo-5-nitro-1,3-dioxane, an antimicrobial compound, is effective against Gram-positive and Gram-negative bacteria and fungi, including yeast. 5-Bromo-5-nitro-1,3-dioxane inhibits enzyme activity and subsequent inhibition of microbial growth by the oxidation of essential protein thiol[1].

Product Specifications

CAS Number

[30007-47-7]

UNSPSC

12352005

Hazard Statement

H302, H314, H410

Target

Bacterial; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/5-bromo-5-nitro-1-3-dioxane.html

Concentration

10mM

Purity

99.89

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 2 mg/mL (ultrasonic)

Smiles

O=[N+](C1(Br)COCOC1)[O-]

Molecular Formula

C4H6BrNO4

Molecular Weight

212.00

Precautions

H302, H314, H410

References & Citations

[1]M Ghannoum, et al. Mode of Action of the Antimicrobial Compound 5-bromo-5-nitro-1,3-dioxane (Bronidox) . Folia Microbiol (Praha) . 1986;31 (1) :19-31.