MC-VC-PAB-MMAD
Product Specifications
UNSPSC Description
MC-VC-PAB-MMAD is a agent-linker conjugate for ADC with potent antitumor activity by using MMAD (a potent tubulin inhibitor), linked via the cleavable ADC linker MC-VC-PAB[1].
Target Antigen
Drug-Linker Conjugates for ADC; Microtubule/Tubulin
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-vc-pab-mmad.html
Smiles
O=C(C[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@H](C(N(C)[C@H]([C@@H](CC(N2[C@H]([C@@H]([C@H](C(N[C@@H](CC3=CC=CC=C3)C4=NC=CS4)=O)C)OC)CCC2)=O)OC)[C@@H](C)CC)=O)C(C)C)=O)=O)C=C1)=O)=O)CCCCCN5C(C=CC5=O)=O
Molecular Weight
1368.72
References & Citations
[1]Chudasama V, et al. Recent advances in the construction of antibody-drug conjugates. Nat Chem. 2016 Feb;8(2):114-9.
Shipping Conditions
Room temperature
Available Sizes
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