INH6
INH6 is a potent Nek2/Hec1 inhibitor; inhibits the growth of HeLa cells with an IC50 of 2.4 μM.
Product Specifications
CAS Number
[1001753-24-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; NEKs
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/INH6.html
Purity
99.53
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NC1=NC(C2=C(C)C=C(C)C=C2C)=CS1)C3=CC=CC=C3
Molecular Formula
C19H18N2OS
Molecular Weight
322.42
Precautions
H302, H315, H319, H335
References & Citations
[1]Qiu XL, et al. Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analogues. J Med Chem. 2009 Mar 26;52 (6) :1757-67.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NEK2
Available Sizes
Curated Selection
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