Ici 216140
ICI 216140 is a potent GRP/bombesin receptor 2 antagonist with an in vitro IC50 of 2 nM. It inhibits bombesin-stimulated pancreatic amylase secretion in rats at 2 mg/kg and attenuates bombesin-induced blood pressure increases at 1 mM, demonstrating its utility in researching bombesin receptor functions.
Product Specifications
Field of Research
Pharmacology & Drug Discovery
Molecular Weight
916.08
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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