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Ici 216140

ICI 216140 is a potent GRP/bombesin receptor 2 antagonist with an in vitro IC50 of 2 nM. It inhibits bombesin-stimulated pancreatic amylase secretion in rats at 2 mg/kg and attenuates bombesin-induced blood pressure increases at 1 mM, demonstrating its utility in researching bombesin receptor functions.

Product Specifications

Field of Research

Pharmacology & Drug Discovery

Molecular Weight

916.08

Storage Conditions

-20°C

Notes

For research use only.

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