Ac-YVAD-CMK
Ac-YVAD-CMK is a potent, irreversible, and selective caspase-1 inhibitor that effectively blocks pyroptosis and the maturation of IL-1β/IL-18. This neuroprotective and anti-inflammatory compound is widely used in research models, including studies of inflammatory diseases and neuroinflammation in both cellular and animal systems.
Product Specifications
Product Name Alternative
Caspase-1, Caspase-1 Inhibitor II, Ac-YVAD-CMK, Ac-Tyr-Val-Ala-Asp-chloromethylketone, Ac-Tyr-Val-Ala-Asp-CMK, Immunology related, Immunologyrelated, inflammation, Inflammation related, Inflammationrelated, ILReceptor, IL-1β, IL Receptor, Pyroptosis
Field of Research
Cell Biology, Immunology & Inflammation, Protein Biochemistry
Purity
97.08% (May vary between batches)
Solubility
DMF:10 mg/mL (18.48 mM) ; DMSO:90 mg/mL (166.36 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.1 mM)
Molecular Weight
540.99
Storage Conditions
-20°C
Notes
For research use only.
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