Antileukinate
Antileukinate is an acetylated, amidated hexapeptide antagonist of the CXCR2 chemokine receptor. It blocks IL-8 binding and neutrophil activation in vitro (Ki = 2.7-13 μM) and demonstrates protective effects in vivo, such as reducing acute pancreatitis and associated lung injury in mouse models at 53 mg/kg.
Product Specifications
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Molecular Weight
1003.19
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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