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AP 811

AP 811 is a potent and highly selective antagonist of the atrial natriuretic peptide clearance receptor (NPR3), with a Ki of 0.48 nM and >20,000-fold selectivity over NPR1. It blocks ANP-induced cardiac stimulation and is a valuable tool for investigating NPR3 function in cardiovascular and renal physiology, both in vitro and in vivo.

Product Specifications

Field of Research

Pharmacology & Drug Discovery

Molecular Weight

915.11

Storage Conditions

-20°C

Notes

For research use only.

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