AY 254
AY 254 is a potent and biased PAR2 agonist that selectively activates ERK1/2 phosphorylation (EC50 = 2 nM) over calcium mobilization. It facilitates wound healing, inhibits cytokine-induced caspase activation, and stimulates IL-8 secretion in HT29 colorectal cancer cells, supporting research in inflammation and oncology.
Product Specifications
Field of Research
Pharmacology & Drug Discovery
Molecular Weight
631.779
Storage Conditions
-20°C
Notes
For research use only.
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