AY 77
AY 77 is a potent and selective PAR2 agonist, demonstrating differential EC50 values for Ca2+ mobilization (40 nM) and ERK1/2 phosphorylation (2 μM) . This compound has been shown to stimulate the migration of human breast cancer cells in vitro, making it a useful research tool for studying PAR2 signaling in oncology and inflammation.
Product Specifications
Product Name Alternative
AY 77, AY77, AY-77, Ca (2+) receptor, CalciumChannel, Calcium Channel, ERK2, ERK1, PAR2, Proteaseactivated Receptor, ProteaseactivatedReceptor, Unk-Cha-Chg-NH2
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.64% (May vary between batches)
Solubility
Ethanol:0.9 mg/mL (2.22 mM)
Molecular Weight
404.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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