HN252
HN252 is a potent PPM1B inhibitor (Ki= 0.52 µM) [1].
Product Specifications
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/hn252.html
Purity
98.54
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC1=C(C=CC(C2=CC=C(C=C2)C3=CC=C(C(O)=C3)O)=C1)C(O)=O
Molecular Formula
C19H15NO4
Molecular Weight
321.33
References & Citations
[1]Lu Z, et al. Identification of HN252 as a potent inhibitor of protein phosphatase PPM1B. J Cell Mol Med. 2020 Nov;24 (22) :13463-13471.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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