Eukaryotic translation initiation factor 3

Eukaryotic initiation factor 3 (eIF3) is a key protein complex that regulates the initiation of translation. It functions by binding to the 40S ribosomal subunit and mRNA, preventing premature joining of the 60S subunit. This essential factor is widely used in vitro to study translational control mechanisms and in vivo to investigate cellular protein synthesis and related diseases.