H-Dab (Boc) -OH
H-Dab (Boc) -OH is an amino acid derivative with a Boc protecting group, which can be used to synthesize methotrexate (MTX) analogs with antitumor and antifolate activities[1].
Product Specifications
CAS Number
[10270-94-7]
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Amino Acid Derivatives
Type
Peptides
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/h-dab-boc-oh.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C([C@H](CCNC(OC(C)(C)C)=O)N)O
Molecular Formula
C9H18N2O4
Molecular Weight
218.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Rosowsky, et al. "Methotrexate analogs. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogs containing a basic amino acid side chain." Journal of medicinal chemistry 29.5 (1986) : 655-660.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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