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PUMA BH3

The PUMA BH3 peptide is a direct activator of Bak with high affinity (Kd 26 nM) . It mimics the function of the full-length PUMA protein, which is a key mediator of p53-dependent apoptosis through mitochondrial targeting, Bcl-2 binding, and cytochrome c release. This tool peptide is widely used in vitro to study intrinsic apoptosis pathways and Bcl-2 family protein interactions.

Product Specifications

Field of Research

Cell Biology

Molecular Weight

3049.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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