β-CGRP, human TFA (101462-82-2 free base)

β-CGRP is a human calcitonin peptide that signals through the calcitonin receptor-like receptor (CRLR) complexed with receptor activity-modifying proteins (RAMPs) . It exhibits distinct binding affinities, with IC50 values of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 complexes, respectively. This peptide is a key tool for in vitro and in vivo research in neuroscience, vascular biology, and migraine pathophysiology.