Apamin TFA (24345-16-2 free base)

Apamin TFA, a bee venom toxin, is a potent and selective blocker of small-conductance calcium-activated potassium (SK) channels, with highest potency at SK2 subtypes. It is widely used as a pharmacological tool in neuroscience and electrophysiology research to study SK channel function in synaptic plasticity, neuronal excitability, and disease models both in vitro and in vivo.