[ (pF) Phe4]Nociceptin (1-13) NH2

This research peptide is a potent and selective agonist of the nociceptin/orphanin FQ (NOP) receptor, exhibiting over 8000-fold selectivity against classical opioid receptors. It is used in vitro and in vivo to study NOP receptor function in pain modulation, cardiovascular responses, and feeding behavior due to its prolonged pronociceptive, hypotensive, and orexigenic effects.