MLCK inhibitor peptide 18
This cell-permeable small molecule is a potent and selective competitive inhibitor of myosin light chain kinase (MLCK), exhibiting an IC50 of 50 nM. It shows >4000-fold selectivity over CaM kinase II and no activity against PKA, making it a valuable tool for investigating smooth muscle contraction, endothelial barrier function, and cell motility in both cellular and animal models.
Product Specifications
Field of Research
Cell Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Molecular Weight
1324.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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