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K- (D-1-Nal) -FwLL-NH2

This small molecule is a potent and high-affinity inverse agonist of the ghrelin receptor, with Ki values of 4.9 nM and 31 nM in COS7 and HEK293T cells, respectively. It effectively inhibits ghrelin-induced Gq and G13 signaling pathways, making it a valuable tool for investigating metabolic regulation and appetite control in both cellular and animal models.

Product Specifications

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Molecular Weight

902.13

Storage Conditions

-20°C

Notes

For research use only.

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