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187-1, N-WASP inhibitor

This small molecule inhibitor targets N-WASP by locking it in an autoinhibited conformation, thereby blocking PIP2-induced actin polymerization with an IC50 of ~2 μM. It is a valuable research tool for studying cytoskeletal dynamics in vitro and has been used to investigate pathways involving Cdc42 and Arp2/3 complex signaling in cellular models.

Product Specifications

Field of Research

Musculoskeletal & Connective Tissue Research; Pharmacology & Drug Discovery, Signal Transduction

Molecular Weight

1784.13

Storage Conditions

-20°C

Notes

For research use only.

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