187-1, N-WASP inhibitor
This small molecule inhibitor targets N-WASP by locking it in an autoinhibited conformation, thereby blocking PIP2-induced actin polymerization with an IC50 of ~2 μM. It is a valuable research tool for studying cytoskeletal dynamics in vitro and has been used to investigate pathways involving Cdc42 and Arp2/3 complex signaling in cellular models.
Product Specifications
Field of Research
Musculoskeletal & Connective Tissue Research; Pharmacology & Drug Discovery, Signal Transduction
Molecular Weight
1784.13
Storage Conditions
-20°C
Notes
For research use only.
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