Neuropeptide S (Mouse)

This potent and selective small molecule agonist of the Neuropeptide S Receptor (NPSR) exhibits an EC50 of 3 nM, mobilizing intracellular Ca2+ in vitro. It is a valuable research tool for studying arousal, anxiety, and sleep-wake regulation, as demonstrated by its ability to increase locomotion and wakefulness while reducing anxiety-like behaviors in murine models.