[Ala17]-MCH

This compound is a potent and selective agonist of the melanin-concentrating hormone (MCH) receptors, exhibiting higher affinity for the MCH1 receptor (Ki = 0.16 nM) over MCH2 (Ki = 34 nM) . It is a valuable research tool for studying MCH signaling in energy homeostasis, sleep regulation, and mood-related behaviors in both in vitro and in vivo models.