MEN 11270
This potent, conformationally constrained cyclic peptide is a selective B2 bradykinin receptor antagonist (pKi = 10.3) derived from HOE 140. It effectively blocks bradykinin-induced hypotension and bronchoconstriction in vivo and shows high selectivity over 29 other receptors and ion channels, making it a valuable tool for cardiovascular and inflammatory research.
Product Specifications
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Molecular Weight
1299.56
Storage Conditions
-20°C
Notes
For research use only.
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