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CTOP

This small molecule is a potent and selective μ-opioid receptor antagonist (Ki μ=0.96 nM, δ>10,000 nM) . Upon central administration in vivo, it induces behavioral effects. In vitro, it also enhances potassium currents in rat locus coeruleus neurons through a mechanism independent of the μ receptor.

Product Specifications

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Molecular Weight

1062.28

Storage Conditions

-20°C

Notes

For research use only.

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