Calcineurin Autoinhibitory Peptide

This small molecule is a potent and selective calcineurin inhibitor (IC50 ~10 μM), exhibiting no significant activity against PP1, PP2A, or CaM kinase II (IC50 >100 μM) . It is widely used in biochemical and cellular research to investigate calcium-mediated signaling pathways, including T-cell activation and neuronal function, in both in vitro and in vivo models.