Recombinant Swine IL-6 protein (His Tag)

Interleukin-6 (IL-6) is a multifunctional α -helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. It exerts actions through the its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.

MGI; IFNB; IL1F; POIL; IFN-β; Aldesleukin; B-Cell Differentiation Factor (BCDF) ; BSF2; BSF-2; catabolin; CDF; HGF; HPGF; HSF; IFNB2; IFN-β2; IL1B; IL1B1; IL1-BETA; IL1F2; IL2; Lymphokine; MGI-2; POIL2; T-cell Growth Factor (TCGF) ; TCGF; Interleukin-6; IL6; IL-6; Interleukin 6

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.