Recombinant Swine IL-1 alpha protein (His Tag)
Product Specifications
Background
Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.
Abbreviation
IL-1 alpha
Synonyms
Interleukin; Hematopoietin; IL1F1hematopoietin; IL1F; IL-1F; alpha; BAF; Hematopoietin-1; IL1; IL1 alpha; IL-1 alpha; IL1-A; IL-1A; IL1-ALPHA; IL1F1; IL-1F1; IL1F1hematopoietin-1; interleukin 1; interleukin-1 alpha; LAF; LEM; preinterleukin 1 alpha; pro-interleukin-1-alpha; Il1a; FAF; Hematopoietin 1; IL 1 alpha; IL 1A; IL1; IL1 ALPHA; IL1F1; Interleukin 1 alpha; LAF; LEM; Preinterleukin 1 alpha; Il1a
UniProt
P18430
Accession Number
P18430
Expression System
E.coli
Tag
C-His
Sequence
Ser113-Ser270
Applications
Cell culture
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 98 % as determined by reducing SDS-PAGE.
Bioactivity
50
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
19.0 kDa
Observed Molecular Weight
17-25 kDa
Species
Porcine
Available Sizes
Curated Selection
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