D[Cha4]-AVP

This compound is a potent and selective agonist for the human vasopressin V1B receptor, with significantly lower affinity for V1A, oxytocin, and V2 receptors. It effectively stimulates ACTH and corticosterone secretion in research models while demonstrating minimal vasopressor activity in vivo, making it a valuable tool for studying stress physiology and neuroendocrinology.