Recombinant Mouse APN Protein (His Tag)
Product Specifications
Background
ANPEP gene encodes aminopeptidase N (APN) also known as microsomal aminopeptiase, alanyl aminopeptidase, aminopeptidase M, CD13, or membrane protein p161, is a member of the peptidase M1 family. Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. Probably plays a role in regulating growth and differentiation of early B-lineage cells. It also may play a role in the catabolic pathway of the renin-angiotensin system. It degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.
Abbreviation
APN
Synonyms
ANPEP; AP-M; AP-N; APN; Aminopeptidase N; CD13; CD13 antigen; CD13APN; PEPN; PEPNhAPN
UniProt
P97449
Accession Number
P97449
Expression System
HEK293 Cells
Tag
C-His
Sequence
Lys69-Ser966
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
103.6 kDa
Observed Molecular Weight
110-130 kDa
Formulation
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Species
Mouse
Available Sizes
Curated Selection
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