Recombinant SARS-CoV-2 NSP10 Protein (His Tag)
Product Specifications
Background
Nsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral replication and is essential for replication. It plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing.
Abbreviation
NSP10
Synonyms
SARS-CoV 2 GFL; SARS-CoV 2 Growth factor-like peptide; SARS-CoV 2 nsp10
Accession Number
YP_009725306.1
Expression System
E.coli
Tag
N-His
Sequence
Ala1-Gln139
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 80 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
17.9 kDa
Observed Molecular Weight
18 kDa
Formulation
Supplied as a 0.2 μM filtered solution of PBS, 10% Glycerol, pH 7.4.
Species
SARS-CoV-2
Available Sizes
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