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Recombinant SARS-CoV-2 3C-like Proteinase Protein (His Tag)

Product Specifications

Background

The viral main proteinase (M pro , also called 3CL pro), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.

Abbreviation

3C-likease

Synonyms

3CL Proteinase; M Proteinase

Accession Number

P0DTC1

Expression System

E.coli

Tag

N-His

Sequence

Ser3264-Gln3569

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

36.1 kDa

Observed Molecular Weight

33 kDa

Formulation

Supplied as a 0.2 μM filtered solution of PBS, 1 mM EDTA, 10% Glycerol, pH 7.4.

Species

SARS-CoV-2

Available Sizes

Frequently Asked Questions

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