Echistatin
This potent, irreversible αVβ3 integrin antagonist (Ki = 0.27 nM) inhibits osteoclast-mediated bone resorption (IC50 = 0.1 nM) and blocks ADP-induced platelet aggregation by antagonizing αIIbβ3 (GPIIb/IIIa) receptors (IC50 = 30 nM) in vitro, supporting research in osteoporosis and thrombosis.
Product Specifications
Field of Research
Signal Transduction
Molecular Weight
5417.1
Storage Conditions
-20°C
Notes
For research use only.
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